Constrained peptides fill an important area of chemical space between ... for biotechnology applications (molecular detection and gene therapy) combining a computational and/or a laboratory approach.

A team of scientists has developed a groundbreaking approach using specially designed peptides to improve drug formulations.

Cell penetrating peptides expand pivotal roles in oncology, neurology, and immunotherapy, connecting specialized carriers ...

This broad approach, called in vivo cell therapy, has the potential to offer the best of both worlds, with scalability and lower cost, not to mention a better safety profile, while maintaining the ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

This study presents genetic circuits that can detect the glucose uptake rate and dynamically regulate the associated metabolic fluxes and the synthesis ... in vitro and in vivo.

However, before such probes can be used in vivo ... surface and so peptides now seem the most promising approach. The QD probes also need to be pure. Any impurities from the synthesis might ...

Reduced nitric oxide availability has been found in hypothyroidism. Adequate thyroid hormone replacement therapy successfully reduced blood pressure.

Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Institute of Zoology, Guangdong Academy of Sciences, ...

Imagine caring for 25,000 individuals instead of 2000. Dean of Weill Cornell Medicine and provost for medical affairs at Cornell University, Robert Harrington, MD, talks medicine in 2050.