Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

"I wanted to give her tools and things that I've learned that have helped me," Sigler told PEOPLE in a new interview with Applegate this week. "We haven't stopped talking since," ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

Jamie-Lynn Sigler’s 10-Year-Old Son Beau Leaves Hospital 33 Days After ‘Nightmare’ Diagnosis Jamie-Lynn Sigler Reveals Son Beau Has Been Diagnosed with Autoimmune Disorder After Catching a ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

The "Dead to Me" star shared the toll that multiple sclerosis has taken on her body and digestive system since she was ...

Christina Applegate revealed in a new episode of her podcast that she has been hospitalized "upwards of 30 times" due to MS ...

The Sopranos' actress says her own experience coping with MS has helped with her 11-year-old son's remarkable recovery from a rare autoimmune condition Cristina Fisher Jamie-Lynn Sigler's 11-year ...

Christina Applegate says that she’s been in the hospital ‘upwards of 30 times’ because of diarrhea and vomiting ...

Jamie-Lynn Sigler's 11-year-old son Beau was hospitalized for 33 days with a rare autoimmune condition known as acute disseminated encephalomyelitis Sigler says her experience living with MS helped ...