The matrix contains citric acid cycle enzymes and mitochondrial DNA ... patients with PAH and found decreased proteins related to mitochondrial oxidative phosphorylation, ATP production by the Krebs ...

Urinary organic acid analysis disclosed massive excretion of lactate, ketones, and Krebs cycle intermediates ... by spectrophotometric methods as described previously.12 The mitochondrial matrix ...

also known as the Krebs cycle—a vital process in cellular energy production. Central to the dysfunction is the aberrant modification of mitochondrial enzymes by S-nitrosylation, a chemical ...

Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial ...

Researchers from the University of Bergen, for the first time, show how mitochondria act as “reservoirs” to hold NAD, which plays an important role in creating energy in the body. Scientists ...

A mechanistic understanding of how mitochondrial dysfunction contributes to cell growth and tumorigenesis is emerging beyond Warburg as an area of research that is under-explored in terms of its ...

PINK1 accumulates at the surface of damaged mitochondria when the constitutive degradation of PINK in the mitochondrial matrix is inhibited. Subsequent homodimerization of PINK1 on the OMM leads to ...

Tea will be served at 10:45 a.m., immediately preceding the seminar.