A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational ...

The Rice lab of bioengineer Gang Bao and collaborators at Baylor College of Medicine have developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the ...

A new study reveals that even low-dose, chronic exposure to air pollution can trigger liver inflammation, fibrosis, and metabolic disruptions, increasing the risk of fatty liver disease and other ...

A FIT and healthy woman assumed an ache in her chest was caused by an ill-fitting bra – but it was something far more ...

Q4 2024 Management View CEO Brian Goff highlighted the company's strategic focus on expanding the Pyrukynd franchise, with significant growth expected from the potential approval and launch in ...

In eukaryotic cells, the ER is the site of three major physiologic ... factor family that is structurally similar to ATF6, is liver specific and can be detected as early as mid-gestation (33).

A group of researchers in China have looked into the role of apolipoprotein B100 (ApoB100) in ovarian cancer following reports of excessive levels of ApoB100 inducing endoplasmic reticulum stress and ...

Human embryonic kidney (HEK293T), human liver cancer (HepG2), and African green monkey ... the newly synthesized virus particles which are transported from ER and Golgi apparatus to the cell surface ...

This nuanced regulation by VMP1 commits limited activation of UPR yet refrains from UPR hyperactivation, which is crucial for protecting cells from chronic ER stress ... the pathogenesis of ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...