Glycolysis occurs after DC activation ... GlcNAc), which is a very important element for maintaining the expression of transcription factor c-Myc. mTORC1 can induce the expression of c-Myc, which also ...

1 and downregulation of MYC (key regulator of growth and survival ... has been shown to induce epigenetic alterations coupled with aberrant Oxphos and glycolysis, resulting in the depletion of ATP, ...

Instead, since more Myc-PA28g was detected in the cells expressing Flag-C1QBP ... primarily focused on mechanism of glycolytic metabolism and metabolic shift from glycolysis to oxidative ...

Retrospective Analysis of BRCA-Altered Uterine Sarcoma Treated With Poly(ADP-ribose) Polymerase Inhibitors Using pretreatment tumor samples, bulk DNA was analyzed via ...

Circ-PAPPA silencing inhibited the growth and glycolysis of CC cells through upregulating miR-656-3p. GNG5, a target of miR-656-3p, could reverse the impacts of silencing circ-PAPPA on CC cells.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein synthesis is an essential process, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. As a common and severe cerebrovascular disease ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, the damaged heart typically replaces tissue with a collagen-rich scar, due to ...

Objective Dysregulated cellular metabolism is a distinct hallmark of human colorectal cancer (CRC). However, metabolic programme rewiring during tumour progression has yet to be fully understood.

PA28γ has been reported to activate the mTORC1 signaling pathway in hepatocellular carcinoma cells to promote glycolysis and inhibit OXPHOS (Yao et al., 2021). These findings contrast with our study, ...