also known as the Krebs cycle—a vital process in cellular energy production. Central to the dysfunction is the aberrant modification of mitochondrial enzymes by S-nitrosylation, a chemical ...

In M2 macrophages, the Krebs cycle and OXPHOS are intact to drive immunosuppression ... In later phase of infection, M2-like macrophages increase mitochondrial oxidative phosphorylation through AMPK ...

It has been shown that after birth in mammals, the expression of most of the enzymes associated with glycolysis decreases significantly after seven days of life, while most of the enzymes involved in ...

Urinary organic acid analysis disclosed massive excretion of lactate, ketones, and Krebs cycle intermediates ... such an encephalopathic event complicated by multiorgan failure. Mitochondria were ...

Restitution of pyruvate dehydrogenase activity enables the irreversible oxidation of pyruvate to acetyl-CoA, which can then enter the Krebs cycle to initiate normal mitochondrial aerobic metabolism.

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial ...

Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...

Researchers from the University of Bergen, for the first time, show how mitochondria act as “reservoirs” to hold NAD, which plays an important role in creating energy in the body. Scientists ...