BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

Major Finding: Cancer cells transfer mitophagy-resistant mitochondria to tumor-infiltrating lymphocytes (TIL) that impair antitumor activity. Concept: Deubiquitinase USP30 protects cancer cell-derived ...

Results: In this study, we identified the following three molecular subtypes: Quiescent Immune (QI), Mitochondrial Stress Immune (MSI) and Oxidative-Phosphorylation Active Immune (OPAI). The QI ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a condition of the nervous system that can be managed with lifestyle modifications or medications, depending on your individual needs.

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

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The data indicated that PR-364 enhanced the functioning of mitochondria, the small structures in cells that generate energy to power biochemical reactions. Healthy mitochondria are critical ...