The EMBO Journal6d
An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins
Structures with similar topology were obtained after detergent solubilization or after detergent-free extraction using a nanodisc-forming polymer. The lipid domains in these structures display ...
eLife8d
Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes
Experimental design of the smFRET system. A) A single receptor molecule (blue) was labeled with donor (D) and acceptor (A) fluorophores, inserted into a phospholipid (yellow) nanodisc (green), and ...
Frontiers28d
Aclacinomycin enhances the killing effect of allogeneic NK cells on acute myeloid leukemia cells by inducing immunogenic cell death
Introduction: Natural killer (NK) cells, which exert spontaneous cytotoxicity against infectious diseases and cancer, also play an important role in leukemia therapy. Despite the success of NK-based ...
C&EN20d
Native Capillary Nanogel Electrophoresis Assay of Inhibitors of Neuraminidases Derived from H1N1 and H5N1 Influenza A Pandemics
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator.
C&EN14d
Evolution of Mass Spectrometers for High m/z Biological Ion Formation, Transmission, Analysis and Detection: A Personal Perspective
Large Molecule Discovery and Research Data Science, Amgen Research, Amgen, Thousand Oaks, California 91320, United States ...