Germline and somatic sequence variants in non-coding regions can play an important role in cancer. Many different modes of action of non-coding variants are known. For example, point mutations and ...

Figure 1: Distribution of conserved non-genic sequences in the human genome ... This is not surprising; as early as the 1980s, the first examples of pathogenic mutations in distal regulatory ...

One popular pattern spotted in many places is the Fibonacci sequence. You’ve likely encountered it before, perhaps as a spiral graphic often superimposed over images of human ears, hurricanes, or ...

A particularly impressive example of the Fibonacci sequence can be found in the reproduction pattern of bees. Male honey bees, called drones, only have one parent; their family tree reflects a ...

Specific examples of sequence engineering that led to improved expression, duration, and enzymatic activity of target proteins are reported in a study published in Nucleic Acid Therapeutics ...