LuPone has found success on TV, too: as the dutiful mom of a son with Down's Syndrome on "Life Goes On;" on multiple Ryan Murphy shows; and with guest roles on "Oz," "30 Rock" and "Penny Dreadful." ...

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In this exclusive episode, Patti and Alan chat about a plethora ... "30 Rock," "Glee," "American Horror Story," "Girls," "Penny Dreadful," and of course, "Life Goes On." She's a voiceover artist ...