This enzyme links the two stages of cellular respiration: glycolysis and the citric acid cycle. In doing so, pyruvate dehydrogenase helps regulate the metabolic plasticity of cells. The ...

Higher MPC expression resulted in smaller cells, not by increasing TCA cycle flux as observed in other cell types, but instead by redirecting mitochondrial pyruvate metabolism towards gluconeogenesis.

Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both ...

Cellular glycogen was determined according to Gründel et al. (2012) with modifications described by Lucius et al. (2021). During growth experiments, two 5 ml samples of cells were harvested from the ...