This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Examining around 3,000 cells, scientists analysed which genes are active in every single cell and identified 19 different cell types. One dot corresponds to an individual cell. The closer the dots ...

UMAP was used for visualisation purposes. the single-cell data expression matrix was processed with the R packages LIGER20 and Seurat.19 We first normalised the data to account for differences in ...

UMAP plots were generated and colored by expression levels ... LR pair without considering the correlation and high-order interaction patterns in single-cell gene expression data. To analyze the high ...

Data normalization is vital to single-cell sequencing, addressing limitations presented by low input material and various forms of bias or noise present in the sequencing process. Several such ...

Landmark single-cell dataset of one billion cells will be used to train new AI models to advance understanding of cellular ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

BioSkryb Genomics, a Durham company focused on single-cell and ultra-low input multiomics, has introduced a new service called ResolveSEQ MRD, which allows more detailed classification and ...

Just as the human body serves as a habitat for bacteria and other microbes, diverse, tiny organisms known as protists host ...