"Tafazzin protrudes into the intermembrane space from both the outer and inner membranes. To define a protein's function, it is critical to know its location in the cell." ...

Tafazzin might play a "surveillance" role in the mitochondria, the chemists said. The research was funded by the American Heart Association and the National Institutes of Health.

Barth syndrome is a rare condition of lipid metabolism that usually has an effect on the males. It is a genetic disorder that is genetic and is caused by a mutation in the tafazzin gene that can ...

In people with Barth syndrome, however, a crucial mitochondria-housed gene, called tafazzin (TAZ), is mutated. Without TAZ, CL remodeling is stopped in its tracks and harmful lipids accumulate.

Barth syndrome is a rare, genetic disorder that affects males. The condition is caused by mutations in the tafazzin gene, which codes for an enzyme involved in the synthesis of cardiolipin, an ...

In people with Barth syndrome, however, a crucial mitochondria-housed gene, called tafazzin (TAZ), is mutated. Without TAZ, CL remodeling is stopped in its tracks and harmful lipids accumulate.

In a previous study, NYU researchers documented the characteristics of a tafazzin-deficiency in a Drosophila (fruit fly) model of the disease, showing low and abnormal cardiolipin concentration ...

In people with Barth syndrome, however, a crucial mitochondria-housed gene, called tafazzin (TAZ), is mutated. Without TAZ, CL remodeling is stopped in its tracks and harmful lipids accumulate.