Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

More than three years after the Pathways Alliance oilsands group first announced plans for a proposed $16.5-billion carbon capture network in northern Alberta, the consortium still hasn’t given ...

Mainstreaming the below protection principles listed in no particular order of importance will allow to maximize the protection impact of complementary pathways. Complementary pathways help enhance ...

Job Offer stream No Job Offer stream You need to meet the work experience, education and language requirements. Through the EMPP, we’ll waive application and biometric fees for you and your dependants ...

There is substantial evidence for the upregulation of Wnt5a by pathogens which leads to activation of noncanonical signaling in macrophages. It is likely, however, that future studies will reveal a ...