Oxford Bio’s recently-appointed chief executive, Dr Frank Mathias, said buying ABL would contribute to the company’s strategy to transition to a pure-play CDMO focusing on the cell and gene ...

ABL has data showing that ABL301 can penetrate ... as well as a now-defunct alliance between AbbVie and Voyager in 2019, based on gene therapy approaches to target the rogue protein.

Atrial fibrillation (AF) is the most common cardiac arrhythmia with a massive burden on global health. The prevalence of AF increases dramatically with age and can be up to 18% in patients older than ...

ABL and Arg kinases also cause endosomal cathepsin L release ... ACE is an interferon-stimulated gene (ISG) that is expressed mostly in the airway epithelial cells in humans (Blanco-Melo et al., 2020) ...

In addition, SYK mediates differentiation through the adaptor protein SH2-domain-containing leukocyte protein of 65 kDa (SLP65), which induces the activation of IgL gene recombination. Pre-BCR sig ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

Future Microbiol. 2009;4(2):223-240.

The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress ...