Lipid nanoparticle platform delivers mRNA to the brain

The blood–brain barrier (BBB) is meant to protect the ... their function and the brain may substitute its iron through transcytosis of iron-loaded Tf across the brain microvasculature.
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier. In research published in Fluids and Barriers of the CNS, ...
The blood-brain barrier (BBB) is a cellular fortress that regulates what ... Deverman and his team recently transformed that idea into a high-throughput protein assay. 19 To select for capsids ...
ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration ... BBB via a receptor-mediated transcytosis (RMT) receptor ...