In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway remains largely ... morphological changes and late mitochondrial damage but no cytochrome ...

Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the body’s immune response through modulating specific cell signaling ...

"This finding highlights a previously unknown connection between mitochondrial activity, inflammation control and the signaling pathways that regulate it," Chandel said. Overall, the findings ...

However, its role in melanoma tumor growth remains insufficiently explored. This study investigates the inductive effect of itraconazole on autophagy-mediated apoptosis in melanoma cells. Method: ...

The discoveries by CCM Biosciences pertaining to the design of drug candidates that can activate the major mitochondrial pathways regulated by sirtuins, along with the clinical development plan for ...

The integrated stress response (ISR) – comprising the four eIF2α kinases PERK, GCN2, PKR, and HRI – is a prominent stress-responsive signaling pathway that regulates mitochondrial morphology and ...

We offer close to 100 pathway majors that lead from an associate degree at Sinclair to a bachelor's degree at UD. All pathways offer a seamless experience between Sinclair and UD, so you can be ...