Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastomas (GBM) are treated with high ...

Secondly, they secrete cytokines, including TNF-α and IL-12, which subsequently attract and activate CTLs to the tumor microenvironment (42). In summary, engaging the cGAS-STING pathway within the TME ...

Fat necrosis refers to dead or damaged breast tissue that often manifests as a noncancerous lump under the skin. In most cases, these lumps go away on their own and don’t return. Fat necrosis of ...

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This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...

Drug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People’s Republic of China Department of Chemistry, National University of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Barth syndrome (BTHS) is a rare genetic ...

BALTIMORE--(BUSINESS WIRE)--TNF Pharmaceuticals, Inc. (Nasdaq: TNFA) (“TNF” or the “Company”), a clinical stage biopharmaceutical company committed to ...

cGAS-STING pathway is a vital natural sensor of host immunity ... as well as a large number of cell death responses resulting in necrosis and apoptosis. The hepatotoxicity of I/R is caused by complex ...

cGAS is an intracellular innate immune sensor that detects double-stranded DNA. The presence of billions of base pairs of genomic DNA in all nucleated cells raises the question of how cGAS is not ...