Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists like me. Consider muscle movement. Your body ...

part of the tRNA synthetase enzyme family. The lead candidates are part of the company’s portfolio of proprietary chemical scaffolds, which have shown broad activity against the enzyme class in ...

Anti-synthetase syndrome is a subtype of idiopathic inflammatory myopathy, and has clinical features including interstitial lung disease, myositis, Raynaud's phenomenon, arthritis, mechanic's hands, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Diffuse ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

A random of 20 seeds × 3 replications were selected for computation of initial moisture content. The initial moisture content of Q. variabilis seeds (Control) was determined as described in Ganatsas ...

Then, protein bands were washed twice in 25 mM AB. Proteolytic digestion was performed by addition of Trypsin (Promega, Madison, WI), 12.5 ng/µl of enzyme in 25 mM AB and incubated at 37 °C overnight.

The authors present three transgenic models carrying three representative exon deletions of the dystrophin gene. The findings presented are valuable to the field of muscle diseases, particularly ...

Department of Chemistry, University of California, Berkeley, California 94720, United States ...