This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

A study explores how cationic fusogenic liposomes temporarily modify membrane properties during fusion, offering new insights ...

Scientists have uncovered a surprising strategy used by the herpes simplex virus (HSV-1) to reawaken in the body. A new study from the University of Virginia School of Medicine has identified a viral ...

Released mitochondrial DNA (mtDNA) was detected in the cytosol, activating the STING pathway. Triple knockouts, including Stinggt/gt, improved survival and body size, highlighting STING's role in ...

Autophagosomes are double-membraned vesicles that contain cellular material slated to be degraded by autophagy. An isolation membrane or phagophore forms near autophagic cargo and expands until it ...

When these markers are absent, other secondary antibodies, such as anti-soluble liver/pancreas antigen (anti-SLA/LP) and liver cytosol type 1 (anti-LC1), should be tested. It is possible to reach a ...