Deferoxamine mesylate (HY-B0988, MCE) was dissolved properly, and was given by daily intraperitoneal (i.p) injection at the different doses, including 25 mg/kg/day, 50 mg/kg/day, and 100 mg/kg/day.

Whereas, iron chelator deferoxamine mesylate (DFO) remarkably reduced erianin-induced cell death, indicating ferroptosis is the dominated method generated erianin-caused cell death (Figures 2A,B).

In 1963, Ciba introduced a breakthrough product for the treatment of iron and alumium overload called Desferal (chelating agent-deferrioxamine methanesulphonate). In 1929, Sandoz introduced a ...

Marburg virus belongs to the genus Marburgvirus in the family Filoviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates ...

(2) Imatinib is a drug used for certain types of cancer and is marketed as its mesylate salt. It is a tyrosine kinase inhibitor and one of the first molecularly targeted therapies used in clinical ...

Mitochondrial dysfunction is involved in numerous diseases and the aging process. The integrated stress response (ISR) serves as a critical adaptation mechanism to a variety of stresses, including ...