Dermatofibromas, also referred to as fibrous histiocytomas, are common benign growths that present as firm nodules. Lesions are usually less than 1.0 cm ...

Lunit SCOPE® IO now available to SITC members for AI-powered TME profiling, in a collaborative effort to advance cancer immunotherapy ...

S100a4, also termed FSP-1 (fibroblast-specific protein-1), was previously considered ... and one lobe was filled with 4% paraformaldehyde for histology. Paraffin-embedded sections were stained with ...

First, we present an overview of the histology of the vascular wall and vascular senescence ... predominantly endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and fibroblasts, are ...

Hepatocellular carcinoma continues to pose a diagnostic challenge, particularly in the setting of underlying pathomorphological changes in the liver due to cirrhosis, steatosis, or steatohepatitis.

This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Overuse tendinopathy is problematic to manage clinically. People of different ages with tendons under diverse loads present with varying degrees of pain, irritability, and capacity to function.

Fibroblast-like synoviocytes (FLS) from rats and patients with RA expressing or not Huntingtin-interacting protein 1 (HIP1) were studied for invasiveness, morphology and cell signalling. HIP1 knockout ...

While it has been believed that RA-FLS are generated in the inflamed synovium through transformation or differentiation of existing synovial fibroblasts, recent interest has expanded towards the role ...