BMJ16d
Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?
While it has been believed that RA-FLS are generated in the inflamed synovium through transformation or differentiation of existing synovial fibroblasts, recent interest has expanded towards the role ...
C&EN1mon
Biomimetic Topological Micropattern Arrays Regulate the Heterogeneity of Cellular Fates in Lung Fibroblasts between Fibrosis and Invasion
Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...
Frontiers3mon
Functional analysis of fibroblasts and macrophages in head and neck paragangliomas
Fibroblast cultures were established from HNPGN were analysed ... nature of HNPGNs remains a clinical conundrum as it cannot be determined based solely on histology or current imaging methods. Over 15 ...
BMJ3mon
Imaging mass cytometry-based characterisation of fibroblast subsets and their cellular niches in systemic sclerosis
Objectives Transcriptomic data demonstrated that fibroblasts are heterogeneous with functionally diverse subpopulations. Although fibroblasts are key effector cells of fibrotic diseases such as ...
Frontiers1y
Development of a fibroblast activation protein-targeted PET/NIR dual-modality probe and its application in head and neck cancer
Based on the observation that fibroblast activation protein (FAP ... Squamous cell carcinoma, the most common HNC histology for nearly 90% of HNC malignancies, is among the most lethal cancers, with a ...