The company’s biggest breakthrough so far has been in developing robust drug delivery technology ... which attaches the siRNA to a sugar ligand. This molecule, called GalNAc is able to pass ...

WVE-007 is a novel, long-acting GalNAc-siRNA targeting INHBE mRNA – a genetically validated target that provides a new approach for healthy, sustainable weight loss (fat loss with muscle ...

To overcome these barriers, many siRNA delivery systems have been developed. Among these, lipid-based nanoparticles have great potential owing to their biocompatibility and low toxicity in ...

WVE-007 is a novel, long-acting GalNAc-siRNA targeting INHBE mRNA - a genetically validated target that provides a new approach for healthy, sustainable weight loss (fat loss with muscle ...

WVE-007 is a novel, long-acting GalNAc-siRNA targeting INHBE mRNA – a genetically validated target that provides a new approach for healthy, sustainable weight loss (fat loss with muscle preservation) ...

Ben Hargreaves speaks to Liberate Bio, a company that is hoping to address the delivery issues that could prevent mRNA, as well as siRNA and ASO ... ligands such as GalNAc, transferrin receptor ...

MEDICINE HAT — Landing Zones Canada completes the development and flight test campaign for its Eagle Advanced Payload Delivery System (APDS). The Eagle is a high-altitude balloon-launched APDS.

Finally, lipid NP-based siRNA delivery systems have the potential to achieve multitarget RNAi or synergism with other therapeutic modalities, leading to a more effective treatment efficacy.

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