HUVEC viability was not significantly affected by treatment with 1–30 µM DHA for up to 72 h (Figures 1A–C), while 50 µM DHA, significantly decreased cell viability upon incubation for 48 h or 72 h ...

Introduction: The conserved miR17~92 cluster, is up-regulated in tumors, and its OE promotes tumor angiogenesis and growth. Recent studies indicate that miR92a is anti-angiogenic while the regulation ...

Formation of vessels is a key regulator for the growth of solid tumor. So, angiogenesis inhibitors are very important for the cancer therapy. Tumstatin is a 28 kDa cryptic domain shed from the carboxy ...

The hypoxic microenvironment of rapidly growing ovarian cancer upregulates the transcription factor ELF3 in the tumor cells. ELF3 directly promotes IGF1 transcription, thereby promoting vascular ...

Keywords: sprouting angiogenesis, automated quantification, spheroids, in vitro angiogenesis assay, sprouting parameters Citation: Kannan P, Schain M and Lane DP (2022) An Automated Quantification ...

In contrast, the lungs from patients with influenza had less intussusceptive angiogenesis and no increase over time (Figure 4C). A similar pattern was seen for sprouting angiogenesis (Figure 4D).

Background and Purpose— Bone marrow mononuclear cells (BM-MNCs) are a rich source of hematopoietic stem cells and have been widely used in experimental therapies for patients with ischemic diseases.

A genome-wide phenotype screen was used to identify factors and pathways that induce proliferation of human umbilical vein endothelial cells (HUVEC). HUVEC proliferation is a recognized marker for ...