I f you constantly feel hungry no matter how you try to manage your appetite, a hormonal imbalance known as leptin resistance ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

but have leptin resistance. It remains to be seen if Alnylam's discovery will yield effective treatments, but the potential to treat at-risk individuals who are of normal weight is intriguing ...