A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...

Principles First Founder Heath Mayo discusses the future of the Republican Party and American Principles Project's Terry Schilling discusses this week's Conservative Political Action Conference ...

This results in a decreased expression of proliferation-related genes, including cyclin D1, c-Myc, and c-Fos. Studies have shown that ... of inflammatory cytokines by blocking the PI3K/Akt/mTOR and ...

Author Nigel Hamilton discussed how Presidents Abraham Lincoln and Jefferson Davis American presidents clashed during the Civil War. Porter Square Books in Cambridge, Massachusetts, hosted this ...

Li et al. reported a case of MYC/BCL2/BCL6 triple-hit lymphoma with TP53 mutation that achieved sustained CR for over two years after receving CD19 CAR-T cells infusoin and lenalidomide, suggesting a ...

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may ...