In an article published in the journal Trends in Biochemical Sciences, Alicia Kowaltowski, full professor at the University ...

A paper by scientists affiliated with the University of São Paulo highlights new discoveries regarding the mechanisms of oxidative phosphorylation involved in ATP production. Recent studies have ...

In an article published in the journal Trends in Biochemical Sciences, Alicia Kowaltowski , full professor at the University of São Paulo's ...

Over this time, the mitochondrial genome became reduced, retaining only 37 genes in most animal species, and growing reliant on the nuclear genome to fulfill the organelle’s primary function—to ...

Mitochondria generate ATP through oxidative phosphorylation, and also have a central role in apoptosis. A new study reveals that in drastic contrast to other cancer types, translocation renal cell ...

Acute pancreatitis (AP) is a gastrointestinal disorder characterized by inflammation and necrosis of the pancreatic acinar cells. Mitochondrial homeostasis is key to energy metabolism and redox ...

“We’re using vague terms like mitochondrial dysfunction, and it’s not clear what that means,” said Murphy. Instead, descriptions should focus on the specific process that has gone awry, such as ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...