The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the ...

Trained immunity is reshaping our understanding of host defense by demonstrating that innate immune cells once thought to lack memory can be reprogrammed to mount heightened responses to subsequent ...

This article explores how understanding the brain–immune ecosystem brings insights to the molecular mechanisms behind brain ...

The coronavirus disease 2019 (COVID-19) pandemic underscored the need for the development of tools that can visualize immune system activity in the context of viral inflammation. Although [18F]FDG PET ...

First-in-class dendritic cell (DC) maturation agent Plinabulin drives immune re-sensitization in metastatic NSCLC ...

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), ...

Monte Rosa Therapeutics (GLUE) announced the company will present preclinical data on the potential of MRT-8102 at the American Heart ...

Data support NEK7 as a potential novel and differentiated therapeutic approach to modulate the NLRP3 inflammasome in multiple cardiovascular and cardiometabolic diseases, including pericarditis and ...

Ira Mellman, PhD, President of Research, to receive SITC's Richard V. Smalley Memorial Award for his significant ...

The assay is fast and simple and has already shown clinical utility, although its interpretation may be limited by reference ...

The MarketWatch News Department was not involved in the creation of this content.-- Survival Advantage: Mice treated with Zeta-BC-007 survived beyond 60 days, unlike those receivi ...