Pfizer Inc. (NYSE: PFE) today announced positive topline results from the progression-free survival (PFS) analysis of the Phase 3 BREAKWATER study of ...

If the coadministration cannot be avoided, see the CYP3A4 substrate product labeling for recommendations. Dose reductions of drugs that are substrates of OATP1B1, OATP1B3, or BCRP may be required ...

If the coadministration cannot be avoided, see the CYP3A4 substrate product labeling for recommendations. Dose reductions of drugs that are substrates of OATP1B1, OATP1B3, or BCRP may be required when ...

Hathaway, PhD Prevention of rejection is a primary goal of care of the pancreas transplant recipient ... levels and upward trends in serum amylase, lipase, and glucose levels may be useful ...

causing a change in the enzyme's shape and reducing its activity regardless of substrate concentration. Feedback inhibition is a regulatory mechanism where the end product of a biochemical pathway ...

has granted Orphan Medicinal Product Designation (OMPD) to elraglusib, a novel GSK-3β inhibitor, for the treatment of pancreatic ductal adenocarcinoma (PDAC). “With limited treatment options ...

For the ACE inhibition test, the concentration of the samples GLLGY, HWP, and VYGF was 1 mg/mL, and the concentrations of the substrate FAPGG were 0.2, 0.4, 0.6, 0.8, and 1 mM. For the pancreatic ...

Human α-amylase (A1031), porcine pepsin (P6887), porcine trypsin (T4799), bovine chymotrypsin (C4129), porcine pancreatic lipase (L0382), and fresh bile ... Viable Lactobacilli in the fermented ...