The onset of multiple sclerosis (MS) in older individuals correlates with a higher risk of developing primary progressive MS, faster progression to secondary progressive MS, and increased disability ...

Mucociliary dysfunction, chronic infections with advancing immunosenescence and pulmonary ... Th2-mediated pathways and inflammation, such as CD4 + lymphocytes, mast cells, eosinophils ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

The normal immunosenescence evidenced in both sexes may be modulated in some degree by changing levels and forms of endogenous estrogen. SLE patients have also been evaluated for effect of ...

Consecration and 10 steps to cleansing. They do dovetail with our responsibilities. What is required of a priest and how does the priesthood parallel with those who are Christians? Can you draw a ...

SASP factors are able to induce a senescence phenotype in neighbouring cells. Here we could show that SASP leads to enhanced immunosenescence in the TME of PC. Our results provide a new immunoescape ...