This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Background and Purpose: In the setting of acute ischemic stroke, increased blood-brain barrier permeability (BBBP ... Mann Whitney–U-test to evaluate the difference between groups of continuous ...

If one of the two compared groups did not pass the ... inflammation in EAE and healthy control brain sections as well as the tissue distribution of Eu-VSOP and co-localization with different ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in n.

The Swedish biotech behind a groundbreaking Alzheimer’s treatment is in talks with partners for its new technology that allows drugs to cross the notoriously tricky blood-brain barrier.