Researchers at Oregon Health & Science University have developed the first transgenic nonhuman primate model—genetically ...

Specifically, it suggests that when the nuclear receptor is associated with caveolae membranes or scaffolding protein (see models in Fig. 4Aab), rather than the nucleus, a conformation of the ...

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

Researchers at Brown University and Cincinnati Children’s found that suppressing opsin 3 in the brain of mice makes them eat ...

Scientists discovered years ago that the hypothalamus - which helps to manage body temperature, hunger, sex drive, sleep and more - includes neurons that express the protein opsin 3 (OPN3).

Hy and colleagues compared ProteinReDiff against eight other computational protein design models based on input and output characteristics and improved ligand-binding of proteins from selected ...

Basic science researchers at the Johns Hopkins University School of Medicine are advancing heart health research by finding ...

A new study found that stimulating CB2, a receptor involved in immune cell function, improved cognitive performance in Alzheimer's disease (AD) mouse models. Researchers showed that activating CB2 ...

Announcing a new article publication for BIO Integration journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide, ...

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...