Chimerix holds the potential to have the first approval of dordaviprone for treating recurrent H3 K27M mutant high-grade ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of ...

Cancer arises when your cells grow uncontrollably and refuse to die when they should. Normally, your body is equipped with ...

Immunotherapy is the form of treatment that redirects the immune system toward a pathogen or disease. In many cases, ...

Researchers identify a new player in human immunity that can go rogue and turn the immune system against the body’s own ...

Scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood -- known as the tertiary lymphoid structure -- where they become ...

Cancer cells work together to source nutrients from their environment -- a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Mayo Clinic researchers have discovered a new immunotherapy target, a cryptic antigen, may be key in helping the immune system fight tumors in ovarian cancer.

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

AP2A1 could serve as a biomarker for aging and a target for therapies aimed at slowing down or even reversing the aging ...