The Wilmington High-North Reading swim team competed at the Cape Ann League championship meet prior to the postseason meets ...

People gathered at the RomeRock Association Clubhouse for the 20th annual Polar Bear Plunge Saturday afternoon. The event raises funds for the Pymatuning Valley, Grand Valley and Jefferson school ...

In December 2021, the company was awarded its first four-year from the U.S. Army and Defense Logistics Agency to deploy its surgical C-arm technology at multiple medical treatment facilities.The ...

Taz Skylar, best known for his role as Sanji in Netflix’s One Piece, takes on a completely different character in the new action thriller Cleaner. In the film, Skylar plays Noah, a dangerous member of ...

RICH SQUARE — Leroy Bell, 71, of 4968 Bryantown Road in Rich Square, died Monday, Feb. 10, 2025, at his residence. He was born on April 19, 1953. Funeral services will be held at 11 a.m ...

Ubiquitin-mediated proteasomal degradation is a post-transcriptional protein modification that is comprised of various components including the 76-amino acid protein ubiquitin (Ub), Ub-activating ...

Figure. MST1-Cx43 axis in disturbed flow (d-flow) mediated endothelial cell-cell communication and vascular dysfunction. Key findings show that disturbed flow (d-flow) inhibits MST1 kinase that allows ...

Figure 3 The mechanism of YAP regulation in bladder cancer. a: Mutation of G 12/13 can significantly increase the transcriptional activity of YAP/TAZ by upregulating the RhoGEF-Rho GTPase cascade. b: ...

The YAP and TAZ paralogs are transcriptional co-activators recruited to target sites by TEAD proteins. Here, we show that YAP and TAZ are also recruited by JUNB (a member of the AP-1 family) and STAT3 ...

Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking.