Takeda Pharmaceuticals and Lundbeck have jointly announced the submission of a New Drug Application (NDA) to the US FDA for the investigational agent vortioxetine. Vortioxetine (Lu AA21004 ...

The company is also facing patent expiries for its antidepressant Trintellix/Brintellix (vortioxetine) – for many years its biggest-selling drug – in 2026, while its new top product Rexulti ...

Withdrawal symptoms can vary depending on the antidepressant, and strategies for tapering off the medication may help.

Unlike the current DSM-IV-TR definition of vaginismus, Binik's new conceptualization of vaginismus as a genito–pelvic pain/penetration disorder takes into consideration existing empirical ...

Vaginismus is currently defined as an involuntary vaginal muscle spasm interfering with sexual intercourse that is relatively easy to diagnose and treat. As a result, there has been a lack of ...