Sotorasib - Wikipedia
Sotorasib, sold under the brand names Lumakras and Lumykras, is an anti-cancer medication used to treat non-small-cell lung cancer. [4] [5] It targets a specific mutation, G12C, in the …
Sotorasib for Lung Cancers with KRAS p.G12C Mutation
Jun 4, 2021 · We conducted a multicenter, single-group, open-label, phase 2 trial to evaluate the efficacy and safety of sotorasib as monotherapy in patients with locally advanced or metastatic …
Sotorasib Uses, Side Effects & Warnings - Drugs.com
Sep 11, 2023 · What is sotorasib? Sotorasib is used in adults to treat non-small cell lung cancer who have already been treated with at least one other cancer medicine. Sotorasib is given …
FDA approves sotorasib with panitumumab for colorectal cancer
6 days ago · A total of 160 patients were randomized (1:1:1) to receive either sotorasib 960 mg orally once daily and panitumumab 6 mg/kg IV every 2 weeks, sotorasib 240 mg orally once …
Sotorasib is First KRAS Inhibitor Approved by FDA - NCI
Jun 25, 2021 · FDA has approved the first KRAS-blocking drug, called sotorasib (Lumakras). The approval, which covers the use of sotorasib for some patients with advanced lung cancer, was …
Sotorasib: MedlinePlus Drug Information
Sotorasib is used to treat a certain type of lung cancer (non-small cell lung cancer; NSCLC) that has spread to other parts of the body or cannot be removed by surgery in adults who have …
FDA grants accelerated approval to sotorasib for KRAS G12C …
On May 28, 2021, the Food and Drug Administration granted accelerated approval to sotorasib (Lumakras™, Amgen, Inc.), a RAS GTPase family inhibitor, for adult patients with KRAS …
Sotorasib (oral route) - Mayo Clinic
Sotorasib is used to treat metastatic (cancer that has already spread) or locally advanced (cannot be removed by surgery) non-small cell lung cancer (NSCLC) in patients who have received at …
Sotorasib - NCI - National Cancer Institute
Sotorasib is approved to treat: non-small cell lung cancer (NSCLC) that has spread and has a KRAS p.G12C mutation. It is used in adults who have received at least one other systemic …
Non-Small Cell Lung Cancer (NSCLC) Treatment | LUMAKRAS® (sotorasib)
What is LUMAKRAS ®?. LUMAKRAS ® is a prescription medicine used to treat adults with non-small cell lung cancer (NSCLC) that has spread to other parts of the body or cannot be …