Aug 1, 2020 · This review focuses on the characteristics and applications of biomaterials through the ages, ranging from the prehistoric times to the beginning of the era of modern medicine, which has been arbitrarily set to the middle of the 19th century, when aseptic procedures, antiseptic substances and modern anesthetics were developed.

This essay analyzes the scientific evidence that forms the basis of bioactive materials, covering the fundamental understanding of bioactivity phenomena and correlation with the mechanisms of biocompatibility of biomaterials. This is a detailed ...

Biocompatibility (or tissue compatibility) describes the ability of a material to perform with an appropriate host response when applied as intended. A biocompatible material may not be completely "inert"; in fact, the appropriateness of the host response is decisive.

All materials used in invasive medical device must be biocompatible, and so are biocomposites. Broadly speaking, the biocompatibility can be classified into two kinds, namely, the surface and the structural biocompatibilities.

FDA's Biocompatibility Guidance on Use of ISO 10993-1, I. Introduction. It is the intention of the FDA to assess biocompatibility in a way that is least burdensome for both industry and FDA...

All materials that are nonharmful for the living cells and tissues are known as biocompatible materials and may improve the function of cells in vitro and in vivo. Investigation of materials biocompatibility is one of the most challenging topics in the biomedical field.

Oct 17, 2023 · Is the lack of undesirable effect (e.g., inflammation, immune response) sufficient to determine that a material is biocompatible? What level of adverse effects sets the threshold of nonbiocompatibility and what should be an appropriate timeframe for their evaluation?

Dec 24, 2014 · Biocompatible and biodegradable fusion polymers are a class of new generation of biomaterials that have demonstrated great potential for medical devices, tissue engineering scaffolds, drug...

Oct 25, 2016 · A major research focus is to design biocompatible materials capable of responding to specific biological triggers either for interacting with biological objects or for actuating the release...

If a material is biocompatible, it means that a material does not cause any harmful effects when it is in contact with the body. It also means that the material should perform its specific function without any unplanned effects.

High biocompatibility and functional properties are highly desirable for new biomaterials. The chemical, mechanical, structural properties of biomaterials, their interaction with biological environment or even the methodology of assessment can influence the biocompatibility.

Sep 23, 2021 · To that end, in this Review we describe the concept of performance-advantaged, bio-based polymers (PBPs), highlighting examples wherein superior performance is facilitated by the inherent...

Biocompatible polymers are both synthetic (man-made) and natural and aid in the close vicinity of a living system or work in intimacy with living cells. These are used to gauge, treat, boost, or substitute any tissue, organ or function of the body.

Dec 1, 2024 · The use of modern testing technology and interdisciplinary collaboration will improve evaluation processes even further. This makes it easier to create, optimize, and commercialize eco-friendly and biocompatible materials for a variety of applications.

This article is a review of the concept and evaluation of biocompatibility. It explains how biomaterials change with the development of technology, human changing lifestyles, and needs, and how these materials are developed with the same technology.

Feb 16, 2016 · Biocompatible and biostable polymers are extensively used to package implanted devices, with the main criteria that include gas permeability and water permeability of the packaging polymer to protect the electronic circuit of the …

Mar 20, 2020 · This review focuses on the characteristics and applications of biomaterials through the ages, ranging from the prehistoric times to the beginning of the era of modern medicine, which has been arbitrarily set to the middle of the 19th century, when aseptic procedures, antiseptic substances and modern anesthetics were developed.

Biocompatible materials have been commonly used as antimicrobial agents to sustain the treatment and prevention of peri-implantitis and mucositis of peri-implant.

Feb 4, 2025 · Following these design principles, we propose a pioneering strategy for in situ multiscale dissolving-co-crosslinking of conventional cellulosic paper-based materials in an AlCl 3 /ZnCl 2 aqueous solution at room temperature. This strategy of in-situ dissolving-co-crosslinking can provide multiple nano-level or molecular-level physical entanglements while retaining the …

How biocompatible is the material? It is notable that the quality of “being biocompatible” can be a grey area, where it is not necessarily a matter of either-or. One material can be more biocompatible than another in a specific application, but both can be classified as biocompatible.

Emerging biomaterials for tissue engineering applications witness a multitude of interaction (both along their interface and internally) with human tissue. Insufficient consideration of the spatial and temporal aspects of these biomaterial-tissue interactions often raise biocompatibility concerns.