Zheng-Yi Chen, D.Phil - Harvard University
Dr. Zheng-Yi Chen is an Associate Scientist at Mass Eye and Ear with research interests in the functional genomics of hearing, inner ear hair cell regeneration, mechanisms and treatment for age-related and noise-induced hearing loss, and gene therapy for hereditary deafness.
Zheng-Yi Chen | Harvard Division of Medical Sciences
We use animal models and RNAseq to uncover the pathways involved in different forms of hearing loss due to noise exposure, drug toxicity and aging. The genes and pathways identified serve as potential targets for intervention to treat hearing loss.
Lab Members – Chen Lab - chen-lab.meei.harvard.edu
Associate Professor of Otolaryngology, Harvard Medical School Ph.D., Oxford University Dr. Zheng-Yi Chen’s research interests include the understanding of the causes of hearing loss, the development of treatment by inner ear regeneration, gene editing, and gene therapy.
Zheng-Yi Chen, DPhil (Researcher Profile) | Mass Eye and Ear
Regeneration of these hair cells in the adult mammalian inner ear has been the most prominent obstacle to overcome. Dr. Chen’s laboratory takes a functional genomics approach to systematically study gene expression patterns during mouse inner ear development.
Zheng-Yi Chen | Harvard PhD Program in Neuroscience
We use animal models and RNAseq to uncover the pathways involved in different forms of hearing loss due to noise exposure, drug toxicity and aging. The genes and pathways identified serve as potential targets for intervention to treat hearing loss.
Five Questions with Zheng-Yi Chen - Harvard Catalyst - Harvard …
Oct 28, 2022 · Research by pilot awardee Zheng-Yi Chen, D.Phil may hold the Holy Grail of hearing loss: how to regenerate hair cells, the inner-ear sensory cells that detect sound.
Zheng-Yi Chen | Harvard Catalyst Profiles | Harvard Catalyst
My work involves understanding the molecular basis of genetic deafness. I mapped and cloned one of the first human deafness genes, Norrie disease. I identified an allelic disorder, XFEVR, which is caused by mutations in Norrie gene.
Zheng-Yi Chen - Harvard Brain Science Initiative
The Chen Lab’s research is focused on the following areas: Gene therapy to treat genetic hearing loss. We have developed CRISPR/Cas9-mediated genome editing to treat mouse models of human genetic hearing loss.
Zheng-Yi Chen - Massachusetts Eye and Ear Infirmary/Harvard …
Experience: Massachusetts Eye and Ear Infirmary/Harvard Medical School · Education: Oxford University · Location: Boston · 209 connections on LinkedIn. View Zheng-Yi Chen’s profile on...
- Connections: 209
- Location: Massachusetts Eye and Ear Infirmary/Harvard Medical School
Zheng-Yi Chen, DPhil, Named Principal Investigator on NIH SCGE …
Oct 10, 2024 · Zheng-Yi Chen, DPhil, Associate Professor of Otolaryngology–Head and Neck Surgery at Harvard Medical School and investigator in the Eaton-Peabody Laboratories at Mass Eye and Ear, has been named principal investigator of a $16 million National Institutes of Health (NIH) Somatic Cell Genome Editing grant, focused on Investigational New Drug ...
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